Isn't that full expression "blood of the covenant is thicker than water of the womb"?
Being family doesn't make people automatically relatable or respectful. Time, history, and involvement do.
Involvement is a tricky one. It's not the same as investment. And it can't be too much or too little. There's a Goldilocks zone with it. That Goldilocks zone is also a bit of a moving target.
Estrangement also need not be permanent. And they don't have to resolve with someone being labeled wrong (and coming to correction) and someone being right ("I told you so!") People, children, are not mathematical equations. Sometimes people who love each other just need space to grow on their own or be left alone for a while for whatever reason. Sometimes the best way to love them is to give them that space, and hope that in time, they come back to you.